3 Results for "

Zanthoxylum nitidum (Roxb.) DC.

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Zanthoxylum nitidum (Roxb.) DC." in MCE Product Catalog:

4
Nitidine chloride
Nitidine chloride
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4 Cited Publications
Cat. No.: HY-N0498
CAS No.: 13063-04-2
Category:  

Alkaloids Rutaceae Zanthoxylum nitidum (Roxb.) DC. Plants Disease Research Fields Isoquinoline Alkaloids Inflammation/Immunology

Target:  

Parasite Apoptosis STAT Topoisomerase ERK FAK p38 MAPK NF-κB

Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis, inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A, ERK and c-Src/FAK associated signaling pathway, also has anti-inflammatory activity. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kB pathway .
Nitidine chloride (Standard)
Nitidine chloride (Standard)
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Cat. No.: HY-N0498R
CAS No.: 13063-04-2
Category:  

Alkaloids Rutaceae Zanthoxylum nitidum (Roxb.) DC. Plants Isoquinoline Alkaloids

Target:  

Reference Standards Parasite Apoptosis STAT Topoisomerase ERK FAK p38 MAPK NF-κB

Nitidine (chloride) (Standard) is the analytical standard of Nitidine (chloride). This product is intended for research and analytical applications. Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis, inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A, ERK and c-Src/FAK associated signaling pathway. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kB pathway .
8-Hydroxydihydrochelerythrine
8-Hydroxydihydrochelerythrine
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Cat. No.: HY-N18289
CAS No.: 4070-42-2
Category:  

Alkaloids Other Alkaloids Rutaceae Zanthoxylum nitidum (Roxb.) DC. Plants

Target:  

Cholinesterase (ChE)

8-Hydroxydihydrochelerythrine is a benzophenanthridine alkaloid-derived, selective and competitive AChE inhibitor (IC50=0.61 μM) isolated from the roots of Zanthoxylum nitidum (Roxb.) DC. 8-Hydroxydihydrochelerythrine increases the content of acetylcholine in the synapses of cholinergic neurons and enhances cholinergic neurotransmission. 8-Hydroxydihydrochelerythrine is applicable to the research of neurodegenerative diseases with dementia such as Alzheimer's disease .
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